Structure of PDB 7a79 Chain A

Receptor sequence
>7a79A (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
SMDMPVERILEAELAVETNDPVTNICHAADKQLFTLVEWAKRIPHFSDLT
LEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVG
SIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLR
EKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIG
DTPIDTFLMEMLETP
3D structure
PDB7a79 Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F278 V281 K285 L295 V299 R303 F451 E454 F34 V37 K41 L51 V55 R59 F207 E210
BS02 PLM A I269 A273 Q276 F314 R317 L327 A328 L437 I25 A29 Q32 F70 R73 L83 A84 L193
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7a79, PDBe:7a79, PDBj:7a79
PDBsum7a79
PubMed33187070
UniProtP48443|RXRG_HUMAN Retinoic acid receptor RXR-gamma (Gene Name=RXRG)

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