Structure of PDB 7a78 Chain A

Receptor sequence
>7a78A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
EMPVDRILEAELAVENDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDD
QVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIF
DRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKV
YASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
IDTFLMEMLEAP
3D structure
PDB7a78 Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms.
ChainA
Resolution1.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V351 K355 L365 Q368 V369 R373 T520 F521 E524 E527 V34 K38 L48 Q51 V52 R56 T203 F204 E207 E210
BS02 PLM A A343 Q346 F384 R387 L397 A398 L507 A26 Q29 F67 R70 L80 A81 L190
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7a78, PDBe:7a78, PDBj:7a78
PDBsum7a78
PubMed33187070
UniProtP28702|RXRB_HUMAN Retinoic acid receptor RXR-beta (Gene Name=RXRB)

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