Structure of PDB 7a4p Chain A

Receptor sequence

>7a4pA (length=741) Species: 2649997 (Chlorella ohadii)

KKVKIVVDRNPVATNFEKWAKPGHFSRTLSKGPTTTTWIWNLHADAHDFD
TQTSDLEEISRKVFSAHFGQLGIIFIWLSGMYFHGARFSNYEAWLTDPTH
IKPSAQVVWPIVGQEILNADVGGGFQGLQITSGFFQLWRAAGITSELQLY
TTAIGALVMAAAMFFAGWFHYHKAAPKLEWFQNVESMLNHHLGGLLGLGS
LAWAGHQIHVSLPINKLLDAGVDPKEIPLPHEFTLNPELMAQLYPSFSKG
LAPFFTLDWAQYSDFLTFQGGLNPVTGGLWLTDTVHHHLAIAVLFLIAGH
QYRTNWGIGSSLKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLALF
GSLSIIVAHHMYAMPPYPYLATDYGTQLSLFTHHMWIGGFCIVGAGAHAA
IFMVRDYDPTNNYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHND
TMSALGRPQDMFSDTAIQLQPVFAQWVQNTHFLAPGFTAPNALASTSPSW
GGDVVAVGGKVAMMPISLGTADFLVHHIHAFTIHVTVLILLKGVLYARSS
RLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISIVIFHF
SWKMQSDVWGTVSANGVSHITGGNFAQSANTINGWLRDFLWAQSSQVIQS
YGSALSAYGLIFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVA
PAIQPRALSITQGRAVGVAHYLLGGIATTWSFFLARILAVG

3D structure

• PDB: 7a4p Cryo-EM photosystem I structure reveals adaptation mechanisms to extreme high light in Chlorella ohadii.
• Chain: A
• Resolution: 4.2 Å

Enzymatic activity

• Enzyme Commision number: 1.97.1.12: photosystem I.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CL0	A	Y600 N601 S604 I605 F608 L650 S654 F672 H676 W679 T738 F742	Y590 N591 S594 I595 F598 L640 S644 F662 H666 W669 T728 F732
BS02	CLA	A	L670 L673 G674 H676 F677 A680	L660 L663 G664 H666 F667 A670
BS03	CLA	A	F677 A680 F681 M684 Y692 W693	F667 A670 F671 M674 Y682 W683
BS04	CLA	A	F35 H53 A56 H57 Q62	F25 H43 A46 H47 Q52
BS05	CLA	A	H57 F59 V73 H77 Q80 L81 I84 F85 W349 H350 Q352 L353 N356	H47 F49 V63 H67 Q70 L71 I74 F75 W339 H340 Q342 L343 N346
BS06	CLA	A	Q80 W87 F360 F400	Q70 W77 F350 F390
BS07	CLA	A	W87 S89 G90 F93 H94 F98 W119	W77 S79 G80 F83 H84 F88 W109
BS08	CLA	A	M91 Q116 I140 S142 A667 Y668	M81 Q106 I130 S132 A657 Y658
BS09	CLA	A	Q116 V118 W119 Q124	Q106 V108 W109 Q114
BS10	CLA	A	I15 V17 F74 F78 A176 F179 H180 W190	I5 V7 F64 F68 A166 F169 H170 W180
BS11	CLA	A	T24 N25 F26 K28 W29 H34 K72 S75 G177 W178 Y181 H182	T14 N15 F16 K18 W19 H24 K62 S65 G167 W168 Y171 H172
BS12	CLA	A	V13 I15 W190 S196 H200	V3 I5 W180 S186 H190
BS13	CLA	A	H77 F78 W190 F191 M197 H200 H201	H67 F68 W180 F181 M187 H190 H191
BS14	CLA	A	G152 T162 A212 W213 H216 V220 P240	G142 T152 A202 W203 H206 V210 P230
BS15	CLA	A	G215 I218 H219 F257 G260 L261 F264 L299	G205 I208 H209 F247 G250 L251 F254 L289
BS16	CLA	A	L157 T161 L239 H241 L245	L147 T151 L229 H231 L235
BS17	CLA	A	W269 L276 F278 H296 L299 A300 V303	W259 L266 F268 H286 L289 A290 V293
BS18	CLA	A	F278 D293 T294 H296 H297 A300 I301 H370 M374 T506	F268 D283 T284 H286 H287 A290 I291 H360 M364 T496
BS19	CLA	A	L206 W213 H297 H298 I301 L363 V367 P376 Y377	L196 W203 H287 H288 I291 L353 V357 P366 Y367
BS20	CLA	A	N199 H200 L208 L306 H310 T314 W316 I318	N189 H190 L198 L296 H300 T304 W306 I308
BS21	CLA	A	L202 F305 A308 Y312	L192 F295 A298 Y302
BS22	CLA	A	I307 Q311 G319	I297 Q301 G309
BS23	CLA	A	A328 H329	A318 H319
BS24	CLA	A	H338 L426	H328 L416
BS25	CLA	A	L198 H201 T346 S348 W349 Q352 I355 N356 L359	L188 H191 T336 S338 W339 Q342 I345 N346 L349
BS26	CLA	A	I365 H369 I402 I543 T546 S602	I355 H359 I392 I533 T536 S592
BS27	CLA	A	I366 H370 A373 M374 T506 W510	I356 H360 A363 M364 T496 W500
BS28	CLA	A	W87 T141 S142 T392 H393 W396 I736 W740	W77 T131 S132 T382 H383 W386 I726 W730
BS29	CLA	A	S142 L147 F360 L363 S364 V367 M371 Y377 L390 H393 H394	S132 L137 F350 L353 S354 V357 M361 Y367 L380 H383 H384
BS30	CLA	A	H57 D58 L353 F400 G404 H408 I411 F571 R572 W589	H47 D48 L343 F390 G394 H398 I401 F561 R562 W579
BS31	CLA	A	F333 R429 H433 H440	F323 R419 H423 H430
BS32	CLA	A	H440 W443	H430 W433
BS33	CLA	A	W443 F447 F450 H451	W433 F437 F440 H441
BS34	CLA	A	F450 G454 L455 I457 H458 M462 R467 D470	F440 G444 L445 I447 H448 M452 R457 D460
BS35	CLA	A	W486 T490 H491 A494 T498	W476 T480 H481 A484 T488
BS36	CLA	A	F278 T498 P500 N501	F268 T488 P490 N491
BS37	CLA	A	Y372 F483 V487 Q488 W510 I526 L528 H536 H539 V606 H609	Y362 F473 V477 Q478 W500 I516 L518 H526 H529 V596 H599
BS38	CLA	A	F447 L448 P481 V482 F483 A484 F533 H536 H537	F437 L438 P471 V472 F473 A474 F523 H526 H527
BS39	CLA	A	L441 V444 A540 H544	L431 V434 A530 H534
BS40	CLA	A	I700 H704 V709	I690 H694 V699
BS41	CLA	A	F677 F681 V726 H730 L733	F667 F671 V716 H720 L723
BS42	CLA	A	P332 F333	P322 F323
BS43	PQN	A	W50 M684 F685 W693 A717 L718	W40 M674 F675 W683 A707 L708
BS44	SF4	A	C575 G577 P578 C584	C565 G567 P568 C574
BS45	CLA	A	W50 H704 V709 P711 P715	W40 H694 V699 P701 P705
BS46	CLA	A	I49 W50 L52 H53	I39 W40 L42 H43
BS47	CLA	A	F453 I457 F541 W598 Y731	F443 I447 F531 W588 Y721
BS48	CLA	A	L650 W651	L640 W641
BS49	CLA	A	I446 G449 F450 F453 F541 F597 W598	I436 G439 F440 F443 F531 F587 W588
BS50	CLA	A	F264 F265	F254 F255
BS51	CLA	A	A172 F175	A162 F165

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0009055 electron transfer activity
• GO:0016168 chlorophyll binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0015979 photosynthesis

Cellular Component

• GO:0009507 chloroplast
• GO:0009522 photosystem I
• GO:0009535 chloroplast thylakoid membrane
• GO:0009579 thylakoid
• GO:0016020 membrane

External links

• PDB: RCSB:7a4p, PDBe:7a4p, PDBj:7a4p
• PDBsum: 7a4p
• PubMed: 34462576
• UniProt: W8SY74