Structure of PDB 7a2z Chain A

Receptor sequence
>7a2zA (length=59) Species: 9606 (Homo sapiens) [Search protein sequence]
GVTLFVALYDYEARTEDDLSFHKGEKFQIVNNTEGDWWLAHSLTTGETGY
IPSNYVAPV
3D structure
PDB7a2z Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 6.0
ChainA
Resolution1.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y91 D100 E116 G117 D118 W119 Y132 P134 N136 Y137 Y9 D18 E34 G35 D36 W37 Y50 P52 N54 Y55
External links
PDB RCSB:7a2z, PDBe:7a2z, PDBj:7a2z
PDBsum7a2z
PubMed
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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