Structure of PDB 7a2w Chain A

Receptor sequence
>7a2wA (length=61) Species: 9606 (Homo sapiens) [Search protein sequence]
GGVTLFVALYDYEARTEDDLSFHKGEKFQIVNNTEGDWWLAHSLTTGETG
YIPSNYVAPVD
3D structure
PDB7a2w Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 3.0
ChainA
Resolution0.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y91 D99 D100 E116 G117 D118 W119 Y132 P134 N136 Y137 Y10 D18 D19 E35 G36 D37 W38 Y51 P53 N55 Y56
External links
PDB RCSB:7a2w, PDBe:7a2w, PDBj:7a2w
PDBsum7a2w
PubMed
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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