Structure of PDB 7a1f Chain A

Receptor sequence
>7a1fA (length=329) Species: 9606 (Homo sapiens) [Search protein sequence]
MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYC
SPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHC
PGSVMFLFEGYFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNCN
PALVLPSRQEAAHQIVQLIRKHPQHNIKIGLYSLGKESLLEQLALEFQTW
VVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTHP
TIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSR
RPCGGFQDSLSPRISVPLIPDSVQQYMSS
3D structure
PDB7a1f A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D35 H36 D120 D35 H36 D120
BS02 D5M A T147 Y182 T257 S258 R259 S274 D275 H276 T147 Y182 T257 S258 R259 S274 D275 H276
BS03 D5M A X1 H33 D35 H99 D120 Y182 H276 X1 H33 D35 H99 D120 Y182 H276
External links
PDB RCSB:7a1f, PDBe:7a1f, PDBj:7a1f
PDBsum7a1f
PubMed34387694
UniProtQ9H816|DCR1B_HUMAN 5' exonuclease Apollo (Gene Name=DCLRE1B)

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