Structure of PDB 6zs2 Chain A

Receptor sequence
>6zs2A (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
SMLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYY
ELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYE
DSIVLQSVFTSVRQKIEKEDD
3D structure
PDB6zs2 Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
ChainA
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FX5 A V1484 F1485 L1488 P1489 Y1497 A1536 F1539 N1540 I1546 V36 F37 L40 P41 Y49 A88 F91 N92 I98
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6zs2, PDBe:6zs2, PDBj:6zs2
PDBsum6zs2
PubMed33216538
UniProtP51532|SMCA4_HUMAN Transcription activator BRG1 (Gene Name=SMARCA4)

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