Structure of PDB 6zlk Chain A

Receptor sequence

>6zlkA (length=315) Species: 1053203 (Bacillus cereus HuA2-4) [Search protein sequence]

MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSL
ELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVT
NNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYG
VTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLED
KPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASI
LDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLS
DGLEAEYDYIKQLYK

3D structure

PDB

6zlk Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction.

Chain

Resolution

1.5 Å

3D
structure

Catalytic site residues are labeled in the structure
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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	NAD	A	G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 I124 T126 Y149 K153 Y176 V179 R185 M188	G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 I124 T126 Y149 K153 Y176 V179 R185 M188
BS02	UGA	A	R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276	R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276
BS03	UGB	A	G86 V87 R88 T126 S127 S128 Y149 T178 R185 A189 R192 T204 F206 Q211 R213 I250 E276	G86 V87 R88 T126 S127 S128 Y149 T178 R185 A189 R192 T204 F206 Q211 R213 I250 E276

External links

PDB	RCSB:6zlk, PDBe:6zlk, PDBj:6zlk
PDBsum	6zlk
PubMed	32661196

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