Structure of PDB 6zkw Chain A

Receptor sequence
>6zkwA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEHTQDTELVETRPAGDGTFQKWAAVVVPSG
EEQRYTCHVQHEGLPEPVTLRWKP
3D structure
PDB6zkw Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
ChainA
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 A67 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171 Y6 E62 A66 N76 Y83 W96 H98 F115 S142 K145 E151 Y158 W166 Y170
External links
PDB RCSB:6zkw, PDBe:6zkw, PDBj:6zkw
PDBsum6zkw
PubMed35108401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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