Structure of PDB 6zc4 Chain A

Receptor sequence
>6zc4A (length=88) Species: 9606 (Homo sapiens) [Search protein sequence]
AMSLNIITVTLNMEKYNFLGISIVGQGIYIGSIMKGGAVAADGRIEPGDM
LLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKS
3D structure
PDB6zc4 Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QEZ A N258 F259 L260 G261 I262 I264 L319 N17 F18 L19 G20 I21 I23 L71
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:6zc4, PDBe:6zc4, PDBj:6zc4
PDBsum6zc4
PubMed
UniProtQ92997|DVL3_HUMAN Segment polarity protein dishevelled homolog DVL-3 (Gene Name=DVL3)

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