Structure of PDB 6zbv Chain A

Receptor sequence
>6zbvA (length=539) Species: 9606 (Homo sapiens) [Search protein sequence]
RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFC
GIPAFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVV
ICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDLTHSLQRTSPSEEYW
RLYVLKLSDDIGNFGEVRLPLLGCLGVAWLVVFLCLIRGVVYFTATFPYV
VLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQAFYSLGCA
WGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHL
GVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFC
LLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLL
LMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQIC
WRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIP
LYAMFRLARTDGDTLLQRLKNATKPSRDWGPALLEHRTG
3D structure
PDB6zbv Structural insights into the inhibition of glycine reuptake.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QET A Y116 A117 G119 G121 S371 G373 W376 G378 L379 N386 T472 C475 Y17 A18 G20 G22 S246 G248 W251 G253 L254 N261 T347 C350
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6zbv, PDBe:6zbv, PDBj:6zbv
PDBsum6zbv
PubMed33658720
UniProtP48067|SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (Gene Name=SLC6A9)

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