Structure of PDB 6z55 Chain A

Receptor sequence
>6z55A (length=358) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECL
DHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSD
WFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFL
HENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSA
TFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLF
QTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYV
KENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAG
LTPEERSF
3D structure
PDB6z55 Crystal structure of CLK3 in complex with macrocycle ODS2004070
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.12.1: dual-specificity kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PQ5 A A184 K186 F236 L238 L239 L290 D320 A60 K62 F112 L114 L115 L166 D196
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6z55, PDBe:6z55, PDBj:6z55
PDBsum6z55
PubMed
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

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