Structure of PDB 6z52 Chain A

Receptor sequence
>6z52A (length=354) Species: 9606 (Homo sapiens) [Search protein sequence]
SKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHAR
GKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNF
HGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQ
LTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDH
EHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHE
NREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENC
KPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPE
ERSF
3D structure
PDB6z52 Crystal structure of CLK3 in complex with macrocycle ODS2003136
ChainA
Resolution2.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.12.1: dual-specificity kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Q8T A L162 F167 V170 A184 L239 N242 E245 E287 L290 L34 F39 V42 A56 L111 N114 E117 E159 L162
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6z52, PDBe:6z52, PDBj:6z52
PDBsum6z52
PubMed
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

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