Structure of PDB 6z1m Chain A

Receptor sequence

>6z1mA (length=423) Species: 32630 (synthetic construct)

LKFPKDFLWGAATAAYQIEGAANEDGRGPSIWDTFSHTPGKVHNGDNGDV
ACDHYHRYKEDVELMKELGLNAYRFSISWPRILPEGEGKVNQKGLDFYNN
LIDELLENGIEPFVTLYHWDLPQALQDKGGWENRETVDAFAEYARVCFER
FGDRVKYWITFNEPNVFAVLGYLSGVHPPGMKDLKKAFRAAHNLLLAHAR
AVKAYREISQNGQIGITLNLSPVYPASDNEEEDKAAAERADQFNNWFLDP
IFKGKYEHMLERLGEQIAANGGELPEITDEMEILSASLDFIGLNYYTSNL
TDMGWEIYPEGLYDLLKRIHEKYNLPIYITENGMAVDDEVEDGAVHDTNR
IDYLKEHLEAVHKAIEEGVNVRGYFVWSLMDNFEWANGYSKRFGLIYVDY
KTQKRTPKKSAYWYREVIKSNGL

3D structure

• PDB: 6z1m Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.
• Chain: A
• Resolution: 2.45 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	P172 N173 L202 L203 L226 L228 N252 F255 K261 Y264 L296 R345 Y350	P164 N165 L194 L195 L218 L220 N244 F247 K253 Y256 L288 R318 Y323
BS02	MG	A	H373 K436	H346 K409

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sun Dec 1 01:32:33 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '6z1m', asym_id = 'A', title = 'Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='6z1m', asym_id='A', title='Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004553,0005975,0008422,0030245', uniprot = '', pdbid = '6z1m', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004553,0005975,0008422,0030245', uniprot='', pdbid='6z1m', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>