Structure of PDB 6yz2 Chain A

Receptor sequence
>6yz2A (length=256) Species: 156889 (Magnetococcus marinus MC-1) [Search protein sequence]
SHMSRKIRDLIESKRFQNVITAIIVLNGAVLGLLTDTTLSASSQNLLERV
DQLCLTIFIVEISLKIYAYGVRGFFRSGWNLFDFVIVAIALMPRTFRIFR
VMRLVSVIPTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLYGAT
FPEWFGDLSKSLYTLFQVMTLESWSMGIVRPVMNVHPNAWVFFIPFIMLT
TLTVLNLFIGIIVDAMAITKEQEEEAKTGHHQEPISQTLLHLGDRLDRIE
KQLAQN
3D structure
PDB6yz2 Cannabidiol interactions with voltage-gated sodium channels.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 2CV A M189 W196 I200 M183 W190 I194
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005261 monoatomic cation channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process

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Cellular Component
External links
PDB RCSB:6yz2, PDBe:6yz2, PDBj:6yz2
PDBsum6yz2
PubMed33089780
UniProtA0L5S6

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