Structure of PDB 6yxk Chain A

Receptor sequence

>6yxkA (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLVQPGAEVMQPGASMKVPCETSGYIFNDYYLHWVRQAPGLGLEWMGWI
APKTGVTKFAQKFQGRVNMTADSSVNTSYLEMTGLTFDDTAVYFCARGTY
LPVDESAAFDVWGLGTDVTVSSASTKGPSVFPLAPSSKSGTAALGCLVKD
YFPEPVTVSWNSGALTSGVHTFPAVLQSSGLFSLSSVVTVPSSSLGTQTY
ICNVNHKPSNTKVDKRVEPK

3D structure

PDB

6yxk Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.

Chain

Resolution

2.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y33 H35 W50 T100 D105 E106 S107 A108	Y32 H34 W49 T99 D104 E105 S106 A107

External links

PDB	RCSB:6yxk, PDBe:6yxk, PDBj:6yxk
PDBsum	6yxk
PubMed	35138894

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