Structure of PDB 6yuf Chain A

Receptor sequence
>6yufA (length=384) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
GRLLRLEVENFKSYRGHQIIGPFEDFTSIIGPNGAGKSNLMDAISFVLGV
KSSHLRSTNVKELIPTTAYVKLMYELDNGEQREYKRAITPSGATEYKIDE
EIVTFSEYCGSLQKENILVRARNFLVFQGDVETIASQSPLELSKLVEQIS
GSLEYKSEYDKSKDEQDKAVNLSAHSFNKKRGINAELRLETVETRLAKLD
EEFAAARKAAKNAKERFNAVKQKRLQKFQAAFSHISEQIDPIYKELTKSP
AFPLGGTAYLTLDDLDEPYLGGIKFHAMPPMKRFRDMDQLSGGEKTMAAL
ALLFAIHSYQPSPFFVLDEIDAALDQTNVTKIANYIRQHASSGFQFVVIS
LKNQLFSKSEALVGIYRDQQENSSRTLSINLEGY
3D structure
PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
ChainA
Resolution3.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T123 F124 T104 F105
BS02 BEF A K38 S39 R57 Q147 D1160 K37 S38 R56 Q128 D318
BS03 ADP A K13 S14 G37 K38 S39 N40 R57 E63 L64 I65 K12 S13 G36 K37 S38 N39 R56 E62 L63 I64
BS04 ADP A K1124 R1127 Q1131 S1133 K282 R285 Q289 S291
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO94383|SMC1_SCHPO Structural maintenance of chromosomes protein 1 (Gene Name=psm1)

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