Structure of PDB 6yub Chain A

Receptor sequence
>6yubA (length=423) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
STQKSLSKEEIERYSRQMIVPGMGKEGQLRLMNAKVLIIGAGGLGCPAAQ
YLAGAGVGTIGIVDGDSVETSNLHRQVAHATKRVGMLKVDSLITHLIEIN
PLPVYVPYRFDLTPQNAAQIIKPWDVILDCTDNPATRYLISDVCVLLGKP
LVSAASVQKSGQLIVLNCPPTPQGVVNKKAAPCYRCCFKKPGIMGPVVGM
MGVAQAGEAIKILVSQLHMPPKEGEEVSPEKNLVQPTLLIYTYDLNSAIG
PYSFRALKMGGRKKDCFACGENSTLTLDGIKSGNPNYVGNMTQSTNLAPE
DRITATAYNEKRRNGELGEHILLDTREKEHFSFGSIPGAVNVPFSKFLVK
ASSIKRPAELLPMQPASDEAPIVVVCRRGQDSQEVVEKLKELGLDNGGKR
KIMDIVGGMKAWRDEVDPDFPFI
3D structure
PDB6yub Molecular basis for the bifunctional Uba4-Urm1 sulfur-relay system in tRNA thiolation and ubiquitin-like conjugation.
ChainA
Resolution2.195 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.80: molybdopterin-synthase adenylyltransferase.
2.8.1.11: molybdopterin synthase sulfurtransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C185 C188 C280 C283 C183 C186 C266 C269
Gene Ontology
Molecular Function
GO:0004792 thiosulfate sulfurtransferase activity
GO:0005524 ATP binding
GO:0008641 ubiquitin-like modifier activating enzyme activity
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
GO:0016783 sulfurtransferase activity
GO:0042292 URM1 activating enzyme activity
GO:0046872 metal ion binding
GO:0061604 molybdopterin-synthase sulfurtransferase activity
GO:0061605 molybdopterin-synthase adenylyltransferase activity
GO:0070566 adenylyltransferase activity
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002143 tRNA wobble position uridine thiolation
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0008033 tRNA processing
GO:0032447 protein urmylation
GO:0034227 tRNA thio-modification
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yub, PDBe:6yub, PDBj:6yub
PDBsum6yub
PubMed32901956
UniProtG0SC54

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