Structure of PDB 6ylr Chain A

Receptor sequence
>6ylrA (length=184) Species: 10090 (Mus musculus) [Search protein sequence]
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQL
SSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWL
ETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR
VYKERLGLPPKIVIGYQSHADTATKSTTKNRFVV
3D structure
PDB6ylr Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation.
ChainA
Resolution2.19545 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OYE A K52 K54 W56 N59 M101 W102 E103 R112 R157 W166 K21 K23 W25 N28 M70 W71 E72 R81 R126 W135
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ylr, PDBe:6ylr, PDBj:6ylr
PDBsum6ylr
PubMed34834356
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

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