Structure of PDB 6yiz Chain A

Receptor sequence
>6yizA (length=211) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
GPRNLRVLLDTAIPPSFCDTVSSVLLDDFNMVSLIRTSPADSLATIKQDN
AEIDIAITIDEELKISRFNQCVLGYTKAFVVAHPQHPLCNASLHSIASLA
NYRQISLGSRSGQHSNLLRPVSDKVLFVENFDDMLRLVEAGVGWGIAPHY
FVEERLRNGTLAVLSELYEPGGIDTKVYCYYNTALESERSFLRFLESARQ
RLRELGRQRFD
3D structure
PDB6yiz A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
ChainA
Resolution2.163 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 OT2 A P104 F107 G164 Y165 K167 L292 R293 G296 R297 R299 P14 F17 G74 Y75 K77 L202 R203 G206 R207 R209
BS02 OT8 A I149 A168 I186 L189 I236 A237 P238 Y258 I263 I59 A78 I96 L99 I146 A147 P148 Y168 I173
BS03 OT2 A R297 F300 R207 F210
External links
PDB RCSB:6yiz, PDBe:6yiz, PDBj:6yiz
PDBsum6yiz
PubMed34165899
UniProtQ9I4X0|MVFR_PSEAE Multiple virulence factor regulator MvfR (Gene Name=mvfR)

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