Structure of PDB 6yii Chain A

Receptor sequence
>6yiiA (length=473) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MSKSWNHDRAAKHIDQKIADVEEITIKDYVRDMSLESIPTSTAYRVDGVH
MYADIMNLEDMLNITAVEGTECHKRTLRFLDQHYRAVKRILNKVDARRVD
FHSQRLHSLFTKPYNTESGAETKRVQRAVATAQLIIDVLAETGDDDEQIP
AAKVRIGIDTGLALAVNNGRSGYREPLFLGDPANHAAKLASNNKARGIYL
TNNARKAIGLAESDEPEKSALTAIEIKACQDAAKLDVTSDEIVEEWREDL
KKNPIGGYQFSRQTPPLRDMDIYSLTPANSKRQEMVSLYADIDGFTAYVA
DHINEKTDDVVRTLHVIRSELERVVTSDFEGRRVRFIGDCVQALSCDGTA
HTTDEEKSVSEATRLAGALRSSFNLAIERLNAEGIETGDLGLAIGFDLGP
IAVTRLGAKGNRVRCAIGRSVIESEKRQCACSGVETAIGQVAYDAASKAV
QNLFGKSRKTSHLDYNEATEALA
3D structure
PDB6yii Crystal structure of a class III adenylyl cyclase-like ATP-binding protein from Pseudomonas aeruginosa.
ChainA
Resolution1.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.26: uridylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A Y52 H107 F178 A183 N184 A187 K188 D291 I292 G294 T296 G338 Y52 H107 F178 A183 N184 A187 K188 D291 I292 G294 T296 G338
BS02 CA A D291 I292 D339 D291 I292 D339
BS03 MG A F454 S457 K459 F454 S457 K459
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004016 adenylate cyclase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction
GO:0051607 defense response to virus
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6yii, PDBe:6yii, PDBj:6yii
PDBsum6yii
PubMed32454240
UniProtP0DV40|PYCC_PSEAI Uridylate cyclase (Gene Name=pycC)

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