Structure of PDB 6ygc Chain A

Receptor sequence
>6ygcA (length=159) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MEIVYKPLDIRNEEQFASIKKLIDADLSEPYSIYVYRYFLNQWPELTYIA
VDNKSGTPNIPIGCIVCKMDPHRNVRLRGYIGMLAVESTYRGHGIAKKLV
EIAIDKMQREHCDEIMLETEVENSAALNLYEGMGFIRMKRMFRYYLNEGD
AFKLILPLT
3D structure
PDB6ygc Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
ChainA
Resolution2.994 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.256: N-terminal methionine N(alpha)-acetyltransferase NatC.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E29 Y31 Y80 G82 E118 Y144 Y145 E29 Y31 Y80 G82 E118 Y144 Y145
BS02 COA A L84 R91 G92 G94 A96 K97 A125 N128 L129 L84 R91 G92 G94 A96 K97 A125 N128 L129
Gene Ontology
Molecular Function
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0120518 peptide-methionine-alpha-N-acetyltransferase activity
Biological Process
GO:0017196 N-terminal peptidyl-methionine acetylation
GO:0032880 regulation of protein localization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0031417 NatC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ygc, PDBe:6ygc, PDBj:6ygc
PDBsum6ygc
PubMed33139728
UniProtQ03503|NAA30_YEAST N-alpha-acetyltransferase 30 (Gene Name=MAK3)

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