Structure of PDB 6ycy Chain A

Receptor sequence
>6ycyA (length=808) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
AVTNEEIKTASKIVRRVSNVEAFDKSGSVFKGYQIWTDISPTIENDPNIM
FVKCVVQQGSKKEKLTVVQIDPPGTGTPYDIDPTHAWNCNSQVDPMSFGD
IGLLNHTNIPCVLDFLKHRYLKNQIYTTAVPLIVAINPYKDLGNTTNEWI
RRYRDTADHTKLPPHVFTCAREALSNLHGVNKSQTIIVSGESGAGKTEAT
KQIMRYFASSKSGNMDLRIQTAIMAANPVLEAFGNAKTIRNNNSSRFGRF
MQLVISHEGGIRYGSVVAFLLEKSRIITQDDNERSYHIFYQFLKGANSTM
KSKFGLKGVTEYKLLNPNSTEVSGVDDVKDFEEVIESLKNMELSESDIEV
IFSIVAGILTLGNVRLIEKAAAIMDEDMGVFNKACELMYLDPELIKREIL
IKVTVAGGTKIEGRWNKNDAEVLKSSLCKAMYEKLFLWIIRHLNSRIEPE
GGFKTFMGMLDIFGFEVFKNNSLEQLFINITNEMLQKNFVDIVFERESKL
YKDEGISTAELKYTSNKEVINVLCEKGKSVLSYLEDQCLAPGGTDEKFVS
SCATNLKENNKFTPAKVASNKNFIIQHTIGPIQYCAESFLLKNKDVLRGD
LVEVIKDSPNPIVQQLFEGQVIEKIAKGSLIGSQFLNQLTSLMNLINSTE
PHFIRCIKPNENKKPLEWCEPKILIQLHALSILEALVLRQLGYSYRRTFE
EFLYQYKFVDIAAAEDSSVENQNKCVNILKLSGLSESMYKIGKSMVFLKQ
EGAKILTKIQREKLVEWENCVSVIEAAILKHKYKQKVNKNIPSLLRVQAH
IRKKMVAQ
3D structure
PDB6ycy Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets.
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A T198 S246 T197 S245
BS02 ADP A N138 P139 K141 S193 G194 G196 K197 T198 E199 N242 N137 P138 K140 S192 G193 G195 K196 T197 E198 N241
Gene Ontology
Molecular Function
GO:0000146 microfilament motor activity
GO:0003774 cytoskeletal motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016459 myosin complex
GO:0020039 pellicle
GO:0070258 inner membrane pellicle complex
GO:0160055 glideosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ycy, PDBe:6ycy, PDBj:6ycy
PDBsum6ycy
PubMed33046215
UniProtQ8IDR3|MYOA_PLAF7 Myosin-A (Gene Name=MyoA)

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