Structure of PDB 6y5e Chain A

Receptor sequence
>6y5eA (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB6y5e Structural mechanism of cGAS inhibition by the nucleosome.
ChainA
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R43 T46 R73 R84 F85 Q86 R117 V118 T119 R5 T8 R35 R46 F47 Q48 R79 V80 T81
BS02 dna A R41 Y42 V47 K65 L66 R3 Y4 V9 K27 L28
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6y5e, PDBe:6y5e, PDBj:6y5e
PDBsum6y5e
PubMed32911482
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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