Structure of PDB 6xzv Chain A

Receptor sequence
>6xzvA (length=236) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMS
WSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMA
ICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPLLYAKMIQKLADL
RSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB6xzv Structural Basis for alpha-Helix Mimicry and Inhibition of Protein-Protein Interactions with Oligourea Foldamers.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I288 E446 I75 E230
BS02 VDX A Y175 L261 S265 R302 S303 S306 W314 C316 V328 H333 H423 Y22 L48 S52 R89 S90 S93 W101 C103 V115 H120 H207 BindingDB: Kd=1200nM,EC50=5.5nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xzv, PDBe:6xzv, PDBj:6xzv
PDBsum6xzv
PubMed32935897
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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