Structure of PDB 6xxr Chain A

Receptor sequence
>6xxrA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVV
GRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANV
FASAMMHALEVL
3D structure
PDB6xxr Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainA
Resolution1.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M14 Y16 W23 K69 N71 F77 Q79 R81 V86 M15 Y17 W24 K70 N72 F78 Q80 R82 V87
External links
PDB RCSB:6xxr, PDBe:6xxr, PDBj:6xxr
PDBsum6xxr
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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