Structure of PDB 6xwl Chain A

Receptor sequence
>6xwlA (length=471) Species: 508771 (Toxoplasma gondii ME49) [Search protein sequence]
ADGPYSGILDSVLDAIGNTPMVRMKRLAKVYGLECDLLAKCEFMSAGGSV
KDRIGKAMVEKAEREGRLKAGDTLIEPTSGNTGIGLALAAAVRGYRMIVT
MPAKMSAEKSNIMKCLGAEIVRTPTEAAWNDENSHMGVAAKLQRELENAH
ILDQYNNTANPMVHYDVTAEEIITQCDGDIDMVVIGAGTGGTITGIGRKI
KERCPKCKVVGVDPKGSILAVPDSLNDEKRLQSYEVEGIGYDFVPGVLDR
KVVDEWVKVGDAESFTTARAIIRNEGLFVGGSSGANVWGALQAARQLKKG
QKCVVLLPDSSRNYMSKFISDEWMAEHGFAPEDGAKVKEREKQFGGARIR
DLLSETGATSDVPFVTARLSVEDVIKMMHETKVKEVIVTELVGVLSEDHI
AHSLQSGRCAMQSPVKDIAFKKLAKALPSAYLRDVAKALDFSPYVCVMDE
CPHFLGVITRIDLLHWLATKQ
3D structure
PDB6xwl Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii .
ChainA
Resolution3.201 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.22: cystathionine beta-synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A K56 N86 G193 T194 T197 G243 S287 P313 D314 K51 N81 G188 T189 T192 G238 S282 P308 D309
Gene Ontology
Molecular Function
GO:0004122 cystathionine beta-synthase activity
GO:0016829 lyase activity
Biological Process
GO:0006534 cysteine metabolic process
GO:0006535 cysteine biosynthetic process from serine
GO:0009069 serine family amino acid metabolic process
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019344 cysteine biosynthetic process
GO:0044272 sulfur compound biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xwl, PDBe:6xwl, PDBj:6xwl
PDBsum6xwl
PubMed34194677
UniProtA0A125YSJ9

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