Structure of PDB 6xq8 Chain A

Receptor sequence
>6xq8A (length=205) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPLRTAPIQ
PRVWE
3D structure
PDB6xq8 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainA
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 V6M A E50 K52 R98 Q100 K110 S111 N112 E31 K33 R79 Q81 K91 S92 N93
BS02 V6P A R48 L49 E50 Q100 R29 L30 E31 Q81
External links
PDB RCSB:6xq8, PDBe:6xq8, PDBj:6xq8
PDBsum6xq8
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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