Structure of PDB 6xq7 Chain A

Receptor sequence
>6xq7A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRA
LRTAPIQPRVWE
3D structure
PDB6xq7 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 V6V A V78 L79 P80 V59 L60 P61
BS02 V6V A R48 L49 Q100 A101 R29 L30 Q81 A82
External links
PDB RCSB:6xq7, PDBe:6xq7, PDBj:6xq7
PDBsum6xq7
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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