Structure of PDB 6xq5 Chain A

Receptor sequence
>6xq5A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRA
LRTAPIQPRVWE
3D structure
PDB6xq5 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 V6M A E50 K52 R98 C99 Q100 K110 S111 N112 E31 K33 R79 C80 Q81 K91 S92 N93
External links
PDB RCSB:6xq5, PDBe:6xq5, PDBj:6xq5
PDBsum6xq5
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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