Structure of PDB 6xq1 Chain A

Receptor sequence
>6xq1A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGG
GPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQ
IPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEK
GVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRA
LRTAPIQPRVWE
3D structure
PDB6xq1 A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
ChainA
Resolution1.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 V74 A R48 L49 E50 K52 R98 Q100 K110 R29 L30 E31 K33 R79 Q81 K91
External links
PDB RCSB:6xq1, PDBe:6xq1, PDBj:6xq1
PDBsum6xq1
PubMed34156100
UniProtQ15109|RAGE_HUMAN Advanced glycosylation end product-specific receptor (Gene Name=AGER)

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