Structure of PDB 6xpd Chain A

Receptor sequence
>6xpdA (length=303) Species: 9606 (Homo sapiens) [Search protein sequence]
HCHSGEKGANEYAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAA
HLLINLTSFLLSLFSLWLSSKPPSKRLTFGWHRAEILGALLSILCIWVVT
GVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIVLTVVLHQANASVRA
AFVHALGNLFQSISVLISALIIYFKPEYKIADPICTFIFSILVLASTITI
LKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILS
AHVATAASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQDPDCLFCED
PCD
3D structure
PDB6xpd Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H52 H54 H1 H3
BS02 ZN A H301 H318 E352 H235 H252 E286
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xpd, PDBe:6xpd, PDBj:6xpd
PDBsum6xpd
PubMed32723473
UniProtQ8IWU4|ZNT8_HUMAN Proton-coupled zinc antiporter SLC30A8 (Gene Name=SLC30A8)

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