Structure of PDB 6xpa Chain A

Receptor sequence
>6xpaA (length=296) Species: 116188 (Streptomyces coeruleorubidus) [Search protein sequence]
EGRMQIDEQPGNAIGAAVEGFDHATASDADIDALKSTIYTKKIAVLKGQD
LSPQQFLALGKRLGRPEAYYEPMYQHPEVTEIFVSSNVPENGKQIGVPKT
GKFWHADYQFMPDPFGITLIYPQVIPEKNRGTYFIDMGRAYDRLPEDLKK
EISGTYCRHSVRKYFKIRPHDVYRPISEIIEEVERKTPAVVQPTTFTHPM
TGETVLYISEGFTVGIEDQDGKPLDEELLKRLFDATGQLDESFEHDNIHL
QSFEQGDLLVWDNRSLIHRARHTTTPEPTVSYRVTVHDERKLHDGI
3D structure
PDB6xpa Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H132 D134 H295 R310
Catalytic site (residue number reindexed from 1) H105 D107 H268 R283
Enzyme Commision number 1.14.11.78: (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7UC A Y96 Y101 T127 G128 F130 D134 K193 R310 Y69 Y74 T100 G101 F103 D107 K166 R283
BS02 VVO A H132 D134 H295 R310 H105 D107 H268 R283
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6xpa, PDBe:6xpa, PDBj:6xpa
PDBsum6xpa
PubMed33361191
UniProtA0A3B6UEU3|INLPE_STRC4 (3R)-3-[(carboxymethyl)amino]fatty acid oxygenase/decarboxylase (Gene Name=ScoE)

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