Structure of PDB 6xnc Chain A

Receptor sequence
>6xncA (length=267) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
ERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELG
VPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLM
YANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPI
FICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLK
EYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQM
LAELRSFVSAMKAASRA
3D structure
PDB6xnc Structural Basis of the Stereochemistry of Inhibition of Tryptophan Synthase by Tryptophan and Derivatives.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.20: tryptophan synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1GP A F22 L100 Y175 T183 G184 F212 G213 G234 S235 F21 L99 Y174 T182 G183 F211 G212 G233 S234
Gene Ontology
Molecular Function
GO:0004834 tryptophan synthase activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0000162 tryptophan biosynthetic process
GO:0006568 tryptophan metabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xnc, PDBe:6xnc, PDBj:6xnc
PDBsum6xnc
PubMed33428374
UniProtP00929|TRPA_SALTY Tryptophan synthase alpha chain (Gene Name=trpA)

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