Structure of PDB 6xkb Chain A

Receptor sequence
>6xkbA (length=136) Species: 9606 (Homo sapiens) [Search protein sequence]
GMDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEK
FIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYL
YLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMA
3D structure
PDB6xkb Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I21 S22 R23 M26 K31 Y64 D67 S68 R71 Q72 H75 R112 L116 I22 S23 R24 M27 K32 Y65 D68 S69 R72 Q73 H76 R113 L117
BS02 peptide A K41 Q45 R87 K42 Q46 R88
External links
PDB RCSB:6xkb, PDBe:6xkb, PDBj:6xkb
PDBsum6xkb
PubMed34897689
UniProtO95104|SCAF4_HUMAN SR-related and CTD-associated factor 4 (Gene Name=SCAF4)

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