Structure of PDB 6xh2 Chain A

Receptor sequence
>6xh2A (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
AVPETRPNHTIYINNLNSKIKKDELKKSLHAIFSRFGQILDILVPRTRTP
RGQAFVIFKEVSSATNALRSMQGFPFYDKPMAIQYAKTDKRIP
3D structure
PDB6xh2 Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
ChainA
Resolution1.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A A2 Y13 K22 K23 R47 R49 R52 Q54 Q85 A87 K88 A1 Y12 K21 K22 R46 R48 R51 Q53 Q84 A86 K87
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6xh2, PDBe:6xh2, PDBj:6xh2
PDBsum6xh2
PubMed33051202
UniProtP09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein A (Gene Name=SNRPA)

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