Structure of PDB 6xh0 Chain A

Receptor sequence
>6xh0A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
GTRPNHTIYINNLNSKIKKDELKKSLHAIFSRFGQILDILVPRRRTPRGQ
AFVIFKEVSSATNALRSMQGFPFYDKPMAIQYAKTDR
3D structure
PDB6xh0 Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A Y13 K23 R47 R48 R49 R52 Q54 Y86 A87 K88 Y9 K19 R43 R44 R45 R48 Q50 Y82 A83 K84
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6xh0, PDBe:6xh0, PDBj:6xh0
PDBsum6xh0
PubMed33051202
UniProtP09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein A (Gene Name=SNRPA)

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