Structure of PDB 6xg8 Chain A

Receptor sequence

>6xg8A (length=401) Species: 203119 (Acetivibrio thermocellus ATCC 27405) [Search protein sequence]

IITPEKKELIRNLISEYNITSAKDLQEALKDLLGDTIQNMLEAELDEHLG
YEKYESTEEAKSNYRNGYTSKTLKSSVGQVEIDIPRDRNAEFEPKIVPRY
KRDISEIENKIIAMYARGMSTREINEQIQEIYGFEVSAEMVSKITDKILP
EIEEWQKRPLGEVYPIVFIDAIHFSVKNDGIVGKKAVYIVLAIDIEGQKD
VIGIYVGENESSKFWLSVLNDLKNRGVKDILILCADALSGIKDAINAAFP
NTEYQRCIVHQIRNTLKYVSDKDRKEFARDLKRIYTAPNEKAGYDQMLEV
SEKWEKKYPAAMKSWKSNWDVICPFFKYSEELRKIMYTTNTIESLNSSYR
RINKSRTVFPGDQSLLKSIYLATVKITSKWTMRYKNWGLILGQLQIMFEG
R

3D structure

PDB

6xg8 Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y56 K58 Y59 Y69 R70 N71 G72 Y73 Y105 R107 S142 E144 M145 G185 V187 V363	Y51 K53 Y54 Y64 R65 N66 G67 Y68 Y100 R102 S137 E139 M140 G180 V182 V358
BS02	dna	A	Y59 N71 K76 T77 R91 R93 R104 Y105 R107 Y120 S125 T126 R127 E144 S147 S360 R361 P365 S369 K372	Y54 N66 K71 T72 R86 R88 R99 Y100 R102 Y115 S120 T121 R122 E139 S142 S355 R356 P360 S364 K367

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004803	transposase activity

	Biological Process
GO:0006310	DNA recombination
GO:0006313	DNA transposition
GO:0032196	transposition

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6xg8, PDBe:6xg8, PDBj:6xg8
PDBsum	6xg8
PubMed	33006208
UniProt	A3DBR0

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