Structure of PDB 6xg6 Chain A

Receptor sequence
>6xg6A (length=607) Species: 1314,9606 [Search protein sequence]
PLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISN
ASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELV
SNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYS
RSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEAR
VRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGEWQHEEFYRYVA
QAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSVALYSRKVLIQTKATDIL
PKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQS
KKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQL
TSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQ
FDELTLLHLREFDKKKLISVETDIECLSEKETEELMAWMRNVLGSRVTNV
KVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPR
HALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELL
VKALERH
3D structure
PDB6xg6 General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N119 A123 D158 M163 S178 G179 G199 G202 V203 G204 F205 T251 N50 A54 D89 M94 S109 G110 G130 G133 V134 G135 F136 T182
BS02 BEF A F201 G202 V203 G204 R402 F132 G133 V134 G135 R322
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0019901 protein kinase binding
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0009386 translational attenuation
GO:0060255 regulation of macromolecule metabolic process
GO:0061077 chaperone-mediated protein folding
GO:1901856 negative regulation of cellular respiration
GO:1903427 negative regulation of reactive oxygen species biosynthetic process
GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xg6, PDBe:6xg6, PDBj:6xg6
PDBsum6xg6
PubMed32913054
UniProtQ12931|TRAP1_HUMAN Heat shock protein 75 kDa, mitochondrial (Gene Name=TRAP1);
Q8G9G1

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