Structure of PDB 6xbb Chain A

Receptor sequence

>6xbbA (length=418) Species: 463191 (Streptomyces sviceus ATCC 29083) [Search protein sequence]

PSTVHDFVGIGLGPFNLGLACLTEPIDELDGIFLESKPDFEWHAGMFLDG
AHLQTPFMSDLVTLADPTSPYSFLNYLKEKGRLYSFYIRENFYPLRVEYD
DYCRWAANKLSSIRFGTTVTEVRYEDDLYVVTTSAGDVYRARHLVLGTGT
PPYIPEACQGLDGDFIHNSRYVQHRSELVKKESITIVGSGQSAAEIYQDL
LGEIDVHGYRLNWVTRSPRFFPLEYTKLTLEMTSPEYIDYYRELPEATRY
RLTAEQKGLFKGIDGDLINEIFDLLYQKNLAGPVPTRLLTNSSLNSARHE
NGTYTLAFRQEEQGKDFEIESQGLVLATGYKYAEPEFLAPVKDRLVYDSQ
GNFDVSRAYAIDVTGRGVFLQNAGVHTHSITSPDLGMGAYRNSCIIRELL
GTEYYPVEKTIAFQEFSV

3D structure

PDB

6xbb Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus.

Chain

Resolution

2.366 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

1.14.13.59: L-lysine N(6)-monooxygenase (NADPH).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G18 G20 P21 F22 E42 S43 K44 W49 H50 L60 Q61 V126 G154 T155 G156 Y337 F344 N379 P390 D391 L392	G11 G13 P14 F15 E35 S36 K37 W42 H43 L53 Q54 V119 G147 T148 G149 Y330 F337 N372 P383 D384 L385
BS02	NAP	A	H59 L60 Q61 R103 P162 G195 S196 G197 Q198 S199 R223 S224 K264 F267 K268 A334 T335	H52 L53 Q54 R96 P155 G188 S189 G190 Q191 S192 R216 S217 K257 F260 K261 A327 T328

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0047091	L-lysine 6-monooxygenase (NADPH) activity

	Biological Process
GO:0009058	biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6xbb, PDBe:6xbb, PDBj:6xbb
PDBsum	6xbb
PubMed	33784308
UniProt	B5HNG5

[Back to BioLiP]