Structure of PDB 6x7q Chain A

Receptor sequence
>6x7qA (length=212) Species: 562 (Escherichia coli) [Search protein sequence]
NYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLKKSLDDSAYKFY
PVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPQFTVFHQETETFSALS
CPYSSDIDQFMVNYLSVMERYKSDTKLFPQGVTPENHLNISALPWVNFDS
FNLNVANFTDYFAPIITMAKYQQEGDRLLLPLSVQVHHAVCDGFHVARFI
NRLQELCNSKLK
3D structure
PDB6x7q Structures of chloramphenicol acetyltransferase III and Escherichia coli beta-keto-acylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(de-thia)CoA
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.28: chloramphenicol O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UTA A K49 F50 Y51 T88 F90 F97 A143 L144 P145 W146 A170 K171 Y172 K48 F49 Y50 T87 F89 F96 A142 L143 P144 W145 A169 K170 Y171
BS02 ZN A E18 H22 E17 H21
BS03 CLM A Y20 H189 Y19 H188
BS04 CLM A F129 L154 Y162 I166 F128 L153 Y161 I165
Gene Ontology
Molecular Function
GO:0008811 chloramphenicol O-acetyltransferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6x7q, PDBe:6x7q, PDBj:6x7q
PDBsum6x7q
PubMed
UniProtP00484|CAT3_ECOLX Chloramphenicol acetyltransferase 3 (Gene Name=cat3)

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