Structure of PDB 6x2h Chain A

Receptor sequence
>6x2hA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
FKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALD
SENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPPQCIMC
VNYVLSEIE
3D structure
PDB6x2h Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ULD A F244 H248 M252 F254 A277 Y281 M289 H293 Y307 T321 I337 C339 N341 F9 H13 M17 F19 A42 Y46 M54 H58 Y72 T86 I98 C100 N102
External links
PDB RCSB:6x2h, PDBe:6x2h, PDBj:6x2h
PDBsum6x2h
PubMed
UniProtQ99814|EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (Gene Name=EPAS1)

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