Structure of PDB 6x28 Chain A

Receptor sequence
>6x28A (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
FKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALD
SENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPPQCIMC
VNYVLS
3D structure
PDB6x28 Crystal structure of PT2243 bound to HIF2-PasB*:ARNT-PasB* complex
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ULG A F244 H248 A277 Y281 M289 H293 L296 Y307 M309 T321 C339 N341 F9 H13 A42 Y46 M54 H58 L61 Y72 M74 T86 C100 N102 BindingDB: IC50=<5.00nM
External links
PDB RCSB:6x28, PDBe:6x28, PDBj:6x28
PDBsum6x28
PubMed
UniProtQ99814|EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (Gene Name=EPAS1)

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