Structure of PDB 6x21 Chain A

Receptor sequence
>6x21A (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
FKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALD
SENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYPQCIMCVN
YVLSEIE
3D structure
PDB6x21 Crystal structure of PT1673 bound to HIF2a-B*:ARNT-B* complex
ChainA
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UKJ A F244 H248 M252 A277 Y281 M289 S292 V302 S304 Y307 M309 T321 I337 C339 N341 F9 H13 M17 A42 Y46 M54 S57 V67 S69 Y72 M74 T86 I96 C98 N100
External links
PDB RCSB:6x21, PDBe:6x21, PDBj:6x21
PDBsum6x21
PubMed
UniProtQ99814|EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (Gene Name=EPAS1)

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