Structure of PDB 6x1z Chain A

Receptor sequence
>6x1zA (length=329) Species: 2336 (Thermotoga maritima) [Search protein sequence]
HHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEA
EKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHD
WKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEA
LRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQG
REIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEAD
EKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNF
PGYVRVVYEEDSGILPDLMGEIDNLVKIE
3D structure
PDB6x1z Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UL1 A D58 L59 L60 L71 L74 P91 G92 H94 W96 L99 F102 D63 L64 L65 L76 L79 P96 G97 H99 W101 L104 F107
BS02 MG A D58 N93 H180 D63 N98 H185
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0006259 DNA metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6x1z, PDBe:6x1z, PDBj:6x1z
PDBsum6x1z
PubMed33115610
UniProtQ9X1X0|MRE11_THEMA DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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