Structure of PDB 6wyy Chain A

Receptor sequence
>6wyyA (length=315) Species: 160488 (Pseudomonas putida KT2440) [Search protein sequence]
KLANVVILATGGTIAGLGVDKLIAGVPELADIANVRGEQVMQIASESISN
DDLLKLGKRVAELAESKDVDGIVITHGTDTLEETAFFLNLVEKTDKPIVV
VGSMRPGTAMSADGMLNLYNAVAVASDKQSRGKGVLVTMNDEIQSGRDVS
KAVNIKTEAFKSAWGPMGMVVEGKSYWFRLPAKRHTVNSEFDIKQISSLP
QVDIAYGYGNVTDTAYKALAQNGAKALIHAGTGNGSVSSRVVPALQELRK
NGVQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHDLNPQKARILAMVAMT
KTQDSKELQRIFWEY
3D structure
PDB6wyy Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
ChainA
Resolution1.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T20 T100 D101 K173 E294
Catalytic site (residue number reindexed from 1) T13 T78 D79 K151 E272
Enzyme Commision number 3.5.1.38: glutamin-(asparagin-)ase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A G19 T20 S67 E68 G99 T100 D101 G12 T13 S45 E46 G77 T78 D79
Gene Ontology
Molecular Function
GO:0004067 asparaginase activity
GO:0004359 glutaminase activity
GO:0016787 hydrolase activity
GO:0050417 glutamin-(asparagin-)ase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006528 asparagine metabolic process
Cellular Component
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6wyy, PDBe:6wyy, PDBj:6wyy
PDBsum6wyy
PubMed
UniProtQ88K39|ASPQ_PSEPK Glutaminase-asparaginase (Gene Name=ansB)

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