Structure of PDB 6wwb Chain A

Receptor sequence
>6wwbA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
PEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDL
STVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF
EFRYAKMPD
3D structure
PDB6wwb Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
ChainA
Resolution1.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YA3 A W370 P371 L383 N429 H433 V435 M438 W24 P25 L37 N83 H87 V89 M92
External links
PDB RCSB:6wwb, PDBe:6wwb, PDBj:6wwb
PDBsum6wwb
PubMed34614283
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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