Structure of PDB 6ww7 Chain A

Receptor sequence
>6ww7A (length=927) Species: 9606 (Homo sapiens) [Search protein sequence]
EDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEI
LWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWEITL
DSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSI
HYQMVYSYGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHL
SGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGSGFQ
PRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVS
FATTGEKTVAAVMACRNEACFNQTYTINLYLVETGRRLLDTTITFSLEQS
GTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREES
LAEVVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAW
TSHLNIDTLARDEFNLQKMMVMVTASGKLFGIESSSGTILWKQYLPNVKP
DSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAP
PVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELA
PSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSS
EHVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVT
GRIIHSSVQKKAKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQ
YNATAFSSLDRPQLPQVLQQSYIFPSSISAMEATITERGITSRHLLIGLP
SGAILSLPKALLDPRRPEIPTEQSREENLIPYSPDVQIHAERFINYNQTV
SRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYDYVLIS
SVLFGLVFATMITKRLAQVKLLNRAWR
3D structure
PDB6ww7 Structural basis for membrane insertion by the human ER membrane protein complex.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K592 L624 Q625 S668 I669 F670 Y672 V674 N739 T820 A821 F822 K526 L558 Q559 S602 I603 F604 Y606 V608 N673 T754 A755 F756
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6ww7, PDBe:6ww7, PDBj:6ww7
PDBsum6ww7
PubMed32439656
UniProtQ8N766|EMC1_HUMAN ER membrane protein complex subunit 1 (Gene Name=EMC1)

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