Structure of PDB 6wu5 Chain A

Receptor sequence
>6wu5A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
QTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKV
PYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPR
DLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGELSAEEVSLVCEKVLD
EADGDHDGRLSLEDFQNMILRAPDFLSTFHI
3D structure
PDB6wu5 CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
ChainA
Resolution1.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D116 N118 D120 Y122 D127 D112 N114 D116 Y118 D123
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function

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Biological Process
External links
PDB RCSB:6wu5, PDBe:6wu5, PDBj:6wu5
PDBsum6wu5
PubMed34089643
UniProtQ96Q77|CIB3_HUMAN Calcium and integrin-binding family member 3 (Gene Name=CIB3)

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