Structure of PDB 6wtx Chain A

Receptor sequence
>6wtxA (length=445) Species: 666 (Vibrio cholerae) [Search protein sequence]
LHRNSLIVLADVALFLALYHFLPFEHNVVLGISMLAFIAVLWLTEALHVT
VTAILVPVMAVFFGIFETQAALNNFANSIIFLFLGGFALAAAMHHQGLDK
VIADKVLAMAQGKMSVAVFMLFGVTALLSMWISNTATAAMMLPLVLGVLS
KVDADKQRSTYVFVLLGVAYSASIGGIATLVGSPPNAIAAAEVGLSFTDW
MKFGLPTAMMMLPMAIAILYFLLKPTLNGMFELDRAPVNWDKGKVVTLGI
FGLTVFLWIFSSPINAALGGFKSFDTLVALGAILMLSFARVVHWKEIQKT
ADWGVLLLFGGGLCLSNVLKQTGTSVFLANALSDMVSHMGIFVVILVVAT
FVVFLTEFASNTASAALLIPVFATVAEAFGMSPVLLSVLIAVAASCAFML
PVATPPNAIVFASGHIKQSEMMRVGLYLNIACIGLLTAIAMLFWQ
3D structure
PDB6wtx Structural basis for the reaction cycle of DASS dicarboxylate transporters.
ChainA
Resolution3.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NA A S146 S150 N151 G193 G199 S129 S133 N134 G176 G182
BS02 NA A T373 A376 S377 N378 A420 T356 A359 S360 N361 A403
BS03 UB7 A N151 S200 S377 N378 T379 T421 N134 S183 S360 N361 T362 T404
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6wtx, PDBe:6wtx, PDBj:6wtx
PDBsum6wtx
PubMed32869741
UniProtQ9KNE0

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